Perneb was an ancient Egyptian priest and prince. His father was likely the 2nd Dynasty pharaoh Hotepsekhemwy. Perneb's name is preserved on several clay seals found in the gallery tomb B at Saqqara, which is attributed to two kings (pharaohs) at the same time (king Hotepsekhemwy and king Raneb). This circumstance lead to disputes about the family origin of Perneb; it cannot be said for sure whose son he exactly was.

Perneb became known for a very rare and unusual title: he was priest of Sopdu, a deity which was rarely named in early Egypt. His cult center was somewhere in the eastern Nile delta at a city called Iptjw. The exact geographical position of this town is not known. It is also unknown where Perneb was interred.

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