Hotepsekhemwy was the founder of the 2nd Dynasty of Ancient Egypt. The exact length of his reign is not known; the Turin canon suggests an improbable 95 years, while the Ancient Egyptian historian Manetho reports that the reign of "Boëthôs" lasted for 38 years. Egyptologists consider both statements to be misinterpretations or exaggerations. They credit Hotepsekhemwy with either a 25- or a 29-year rule.
The name of Hotepsekhemwy's wife is unknown. A “son of the king” and “priest of Sopdu” named Perneb might have been his son, but since the clay seals providing his name and titles were found in a gallery tomb which is attributed to two kings equally (Hotepsekhemwy and his successor, Raneb), it is uncertain whose son Perneb really was.